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Antimicrobial Resistance

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View our full arsenal of products designed to combat antimicrobial resistance.

HardyCHROM™ CRE

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HardyCHROM™ CRE is a selective and differential chromogenic agar medium intended for the qualitative and presumptive detection from stool specimens of Escherichia coli that are non-susceptible to carbapenems as pink colonies and KES (Klebsiella aerogenes, Klebsiella oxytoca, Klebsiella pneumoniae, Enterobacter cloacae complex, and Serratia marcescens) that are non-susceptible to carbapenems as blue colonies.

HardyCHROM CRE is intended as an aid in the detection, identification of colonization and control of these bacteria in a healthcare setting. HardyCHROM™ CRE is not intended to diagnose infection or guide therapy. Results can be interpreted after incubation for 18-24 hours. Subculture to non-selective medium is required for confirming identification, antimicrobial susceptibility testing and epidemiological typing.

Features and Benefits:

  • Non-susceptible E. coli produces colonies that are rose to magenta in color with darker pink centers.
  • Klebsiella, Enterobacter, and Serratia spp. produce large, dark blue colonies (with or without a pink halo), are presumptive positive for carbapenem non-susceptible KES (Klebsiella aerogenes, Klebsiella oxytoca, Klebsiella pneumoniae, Enterobacter cloacae complex, and Serratia marcescens).
  • Colonies that are not pink to magenta, blue, or blue with pink halos are negative – No carbapenem non-susceptible Escherchia coli or KES detected.

HardyCHROM™ MRSA

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HardyCHROM™ MRSA is a selective and differential chromogenic medium for the qualitative direct detection of nasal colonization by methicillin-resistant Staphylococcus aureus (MRSA). Not intended to diagnose infection or guide therapy.

Features and Benefits:

  • HardyCHROM™ MRSA simplifies the identification of MRSA colonization.
  • MRSA strains grown in the presence of chromogenic substrates produce deep pink to magenta colonies.
  • Selective agents will inhibit non-MRSA strains.
  • Distinct color change read-out at 24 hours.

HardyCHROM™ ESBL

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HardyCHROM™ ESBL is a selective and differential chromogenic medium which is intended for the qualitative and presumptive detection from stool specimens of: 1) Enterobacteriaceae that are potentially non-susceptible to ceftazidime and cefpodoxime; and 2) Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli, Klebsiella pneumoniae and Klebsiella oxytoca.

ESBL or Extended Spectrum Beta Lactamases refer to a group of enzymes produced by some species of bacteria that can mediate the organism’s resistance to one or more broad spectrum penicillins and cephalosporin antibiotics. Hardy Diagnostics is proud to offer this innovative culture media that will help screen ESBL quickly and more efficiently from stool specimen.

Features and Benefits:

  • Results in as little as 18 hours
  • Easy-to-read color development
  • Escherichia coli produce pink colonies
  • Proteus mirabilis produce yellow/gold colonies
  • Klebsiella pneumoniae produce blue colonies

HardyDisk™ AST Disks

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  • Each cartridge contains 50 disks that are spring loaded for smooth and reliable dispensing.

  • Hardy Diagnostics offers a complete line of all commonly used antibiotics including Avycaz, Zerbaxa, Baxdela, Vabomere, Zemdri, Xerava, Nuzyra.

  • Available in single cartridges or packs of five.

  • Compatible with all BBL dispensers.

  • Improved cartridge design to prevent jamming and tearing.

  • HardyDisk™ AST cartridges are packaged in an all new canister that features a desiccant built into the lid.

  • Kirby-Bauer accessories available; Mueller Hinton Agar, McFarland Standard, calipers and much more!

  • “Last disk recognition” marking tells you when to refill the dispenser.

  • FDA cleared!

HardyDisk AST Susceptibility Disks

Performance of HardyDisk Ceftolozane-Tazobactam Compared to Reference Broth Microdilution for Enterobacteriaceae and Pseudomonas aeruginosa Isolates.

Presented at ASM 2018 – Atlanta, GA

 

 

HardyCHROM ESBL Evaluation

Evaluation of HardyCHROM ESBL as a detection method of ESBL-producing Escherichia coli, Klebsiella pneumoniae, and Klebsiella oxytoca: a multi-centric study.

Presented at ASM 2017- New Orleans, Louisiana

view pdf file

The study concludes that HardyCHROM ESBL can be reliably employed as an initial screen for patients harboring Enterobacteriaceae conferring resistance to extended spectrum beta lactamases and 3rd generation cephalosporins.

 

HardyCHROM™ MRSA

Evaluation of Two Types of Chromogenic Media for the Detection of MRSA in Wound Swabs

Presented at ASM 2011 – New Orleans, LA

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The accurate identification of MRSA positive wound swabs was found to be more reliable on the HardyCHROM™ MRSA media within 24 hours in comparison with BBL™ CHROMagar™ MRSA media.

 

Evaluation of HardyCHROM™ MRSA in Comparison with BBL CHROMagar™ MRSA for the Detection of MRSA in Nasal Swabs

Presented at ASM 2010 – San Diego, California

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HardyCHROM™ MRSA was found to be more reliable and had a faster detection time when compared to BBL CHROMagar™ MRSA.

 

Evaluation of Two Chromogenic Media for MRSA Screening from Nasal Swabs

Presented at ASM 2012 – San Fransisco, California

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Bio-Rad MRSASelect and HardyCHROM MRSA accurately detect MRSA isolates from nasal swab specimens. HardyCHROM MRSA performs reliably at 24 hours, and is actually more accurate than a 48 hour interpretation. In our laboratory, visual clarity of the Hardy media was much preferred compared to the Bio-Rad product.