Partnering with microbiologists to diagnose and prevent diseaseTM
Microbytes logo tm

Hardy Logo White

a culture of service…

April, 2015

© 2015, Hardy Diagnostics,

all rights reserved

The Adenna Miracle Glove

What makes the Miracle glove quite possibly the best you have ever worn?
Watch a short 2 minute video about the Miracle Glove and find out.
Order now..
*  *  *

Urology screening
Mac with Cipro

Hardy’s MacConkey with Cipro was designed by Dr. Liss, a urologist who saw the need for a way to screen his prostate biopsy patients for resistant bacteria before the procedure. By detecting these resistant gram negative bacteria, appropriate prophylactic therapy could be initiated prior to the biopsy in order to prevent septicemia.
*  *  *


At last, there is a selective media for Vibrio that will distinguish between all three of the clinically significant pathogens:
  • V. cholerae
  • V. vulnificus
  • V. parahaemolyticus

These three species will react differently to the chromogens in the media and to UV light shined on the plate.
*  *  *

Download Our
Mini Catalogs

Sue catalog cover

No matter what industry you may be in, Hardy has a mini catalog that contains the microbiology products that are needed in your lab.

  • Food and Beverage
  • Veterinary
  • Anaerobic Microbiology
  • Susceptibility Testing
  • Control Organisms
  • Cosmetics
  • Pharmaceuticals
  • Dehydrated Culture Media
  • And more…

View a complete list and download the PDF version.

Request the paper version.

Val catalog cover

*  *  *



Need a workout
at the Brain Gym?

Feel the burn here

“Dead as a Doornail”

This one goes way back…in fact the phrase first appeared in literature in 1350. By the time Shakespeare used it in King Henry VI in 1592, it was widely used and understood.

In medieval times doors were very heavily constructed of horizontal and vertical planks.

To secure the door’s planks, doornails were pounded through both the horizontal and vertical boards, and to provide added strength and to make sure the nails would not fall out over time, the exposed shafts of the nails would be bent back and pounded into the crosspieces.

We must realize that in those days all metal objects, including doornails, were handmade and relatively expensive, and every attempt was made to constantly recycle and reuse these objects. But because bent doornails were difficult to salvage and unbend, they had no afterlife. They were considered “dead.” Dead as a doornail…and hence the expression that is still in use today.

* * *

Attn: Hardy Customers

Teresa at scope

Hardy Diagnostics is an employee owned company. All of us here are involved in continuous improvement projects. Would you be so kind as to fill out a short three question survey to help us improve our service?

PS: There might be a $50 gift card in it for you!

Can you do a Gram Stain without a microscope?


Yes there is a way to determine the Gram reaction biochemically without having to perform the stain. Hardy’s Lanagram tests for the Gram reaction by using aminopeptidase. Lanagram is especially useful for “hard to determine” bacteria and can be finished in as little as five minutes.

The tube on the left shows a Gram negative reaction. The one of the right shows a Gram positive reaction.

*  *  *

Think about it…

The Thinker

* A real psychic should know the winning lottery numbers. So why are they all still working?

* Isn’t Disneyland a people trap operated by a mouse?

* Sooner or later, doesn’t everyone stop smoking?

* Since light travels faster than sound, isn’t that why some people appear bright until you hear them speak?

* Does war determine who’s right, or just who’s left.

* * *

Wisdom to ponder…


384 B.C  ~  322 B.C

His writings cover many subjects – including physics, biology, zoology, metaphysics, logic, ethics, aesthetics, poetry, theater, music, rhetoric, linguistics, politics and government. It has been said that “Aristotle was the first genuine scientist in history… and every scientist is in his debt.”

“A friend to all is a friend to none.”

“Love is composed of a single soul inhabiting two bodies.”

“It is the mark of an educated mind to be able to entertain a thought without accepting it.”

“At his best, man is the noblest of all animals; separated from law and justice he is the worst.”

“Quality is not an act, it is a habit.”

“There is no great genius without a mixture of madness.”

“Mothers are fonder than fathers of their children because they are more certain they are their own.”

“The most perfect political community is one in which the middle class is in control, and outnumbers both of the other classes.”

“All paid jobs absorb and degrade the mind.”

“The young are permanently in a state resembling intoxication.”

*  * * *

Microbytes logo tm
Want to receive the MicroBytes Newsletter at home?

Want to review past issues
of MicroBytes?

Did you know?

Val catalog cover

Hardy Diagnostics…
  • Is celebrating its 35th year of serving microbiologists.
  • Is ISO 13485 certified for the manufacture of medical devices to give you confidence in our products.
  • Offers you detailed technical inserts, comprised of over 4,500 pages of information regarding microbiology.
  • Services over 10,000 labs and maintains a worldwide network of over 65 distributors.
  • Is an Employee-Owned company. “If we act like we own the place…it’s because we do!”

Send a message to the president .

Blue Logo


Hardy Logo White

Micro Musings…

OK…W’e’re in our lab coats.
Now what?

Can bacteria restore priceless works of art?
Find out how Pseudomonas has

been put to work to dissolve

centuries of pollution accumulation.

Optical oddities…

What is it?

Scroll to the bottom of this column for answer.

“Believe half of what you see

and none of what you hear.”

~ Marvin Gaye ~


Find more

of Leigh Rubin’s cartoon humor.

Want to book Leigh as a speaker at your next event?

Listeria Detected in Ice Cream

According to the CDC, an estimated 1,600 illnesses and 260 deaths occur every year in the United States due to listeriosis. In March of this year, the CDC reported an ongoing outbreak of Listeria monocytogenes infections that started in January 2014.

The outbreak consists of two clusters of illnesses that are linked to Blue Bell brand ice cream products. There have been a total of eight cases involving hospitalizations and three deaths in two states.

The first cluster of illnesses was reported from January 2014 through January 2015. All patients were from Kansas and all were hospitalized at a single hospital for unrelated problems before onset of listeriosis. Four of the five patients had consumed milkshakes made at the hospital with a Blue Bell brand ice cream product called “Scoops.” Listeria monocytogenes sequences isolated from these patients were highly related to sequences of Listeria strains isolated from “Scoops” and two other products made on the same line at Blue Bell Creameries’ Texas facility.

All products involved were recalled by Blue Bell Creameries on March 13, 2015. A list of all recalled Blue Bell Creameries products can be found on the CDC’s website .

The three remaining patients were reported from Texas during 2011 through 2014. Like the patients from Kansas, they were all hospitalized before becoming ill. The sequences from the Listeria monocytogenes strains isolated from these patients closely matched strains isolated from ice cream manufactured at Blue Bell Creameries’ Oklahoma facility.

Listeria monocytogenes is a ubiquitous organism and an intracellular pathogen. Notable virulence characteristics include its ability to replicate within host phagocytic cells and to spread from cell to cell by utilizing host actin. Consuming food contaminated with the bacterium is the most common way to acquire listeriosis. At least 90% of listeriosis patients belong to a higher risk group that includes pregnant women, adults 65 and older, and people with weakened immune systems. Listeriosis can have especially devastating consequences in pregnant women and can lead to miscarriage, stillbirth, premature delivery, or life-threatening infection of the newborn.

L. monocytogenes , unlike most other foodborne pathogens, can grow at refrigeration temperatures, making it a particularly important pathogen for manufacturers of ready-to-eat type foods such as deli meats and hot dogs where post-process contamination can be an issue.

Listeria has also been found in uncooked vegetables, unpasteurized milk and dairy products made from unpasteurized milk, certain soft cheeses, and smoked seafood. Foods linked to outbreaks of Listeria in the past have included cantaloupes, ricotta and other soft type cheeses, mung bean sprouts, and apples intended to be used for a prepackaged caramel apple product.

L. monocytogenes colonies turn a turquoise color
on the selective HardyCHROM Listeria plates.

L. monocytogenes is a significant public health concern and should be detected routinely where contamination can lead to risk of spreading the bacterium and causing infection. Isolation and detection of Listeria in food is recommended to be done with products such as Buffered Listeria Enrichment Broth (BLEB), LPM agar (Lithium Chloride Phenylethanol Moxalactam), Modified Oxford Medium, or PALCAM agar. In addition to these widely used products, Hardy Diagnostics also offers HardyCHROM Listeria (Cat No. G317), a chromogenic and selective medium for isolation of Listeria spp .from food and environmental samples, and Compact Dry LS (Cat No. LS100), a shelf stable, sample-ready medium, for the isolation, presumptive identification, and enumeration of Listeria spp. from food and environmental samples.

Alani Barajas

*  *  *

New Reference Guide for

Clinical Microbiologists!

Two new reference guides released!

Gideon Guide to
Antimicrobial Agents, 2015

Useful and practical  information on 303 anti-infective drugs, at your fingertips!

As of 2015, the fields of Clinical Microbiology and Infectious Disease are challenged by over 3,000 species of bacteria, viruses, fungi and parasites. 303 drugs are currently available to battle these pathogens, each with a unique pharmacology, spectrum of activity and testing standards and range of toxicities.

Gideon Guide to Antimicrobial Agents, 2015 contains 875 pages as a 10.95 MB PDF file.  Since this is an e-book, users can rapidly access a specific drug by name or trade name (currently 25,000  listed) using standard search tools.  The text includes drugs which are available in only one or two countries, and rare historical content on agents which have not been used since the 1950’s.

The first of three sections in the book lists drugs by class and indication; the second is an A-to-Z guide by Disease name; and the third an exhaustive description of each individual agent: Mechanism of action, Typical dosage for adult or child, Details of metabolism, elimination and penetration into various body fluids, Toxicity (185 forms of toxicity), Drug-Drug interactions (558 interactive drugs), Spectrum (including Disc zone diameter and breakpoint standards) and Trade names.

Use the temporary code “hardy10” to receive an additional 10% discount.

Gideon Guide to
Medically-Important Yeasts, 2015

The clinical and laboratory characteristics of 119 yeast taxa associated with human specimens.

The book is an A-to-Z reference that summarizes the practical features of all yeasts associated with human medicine.  This exhaustive text includes distinctive laboratory characteristics, ecology and clinical significance, previous taxonomic designations (“synonyms”) and full phenotype (biochemical reactions).

As of 2015, 119 yeast taxa have been associated with human disease.  The advent of Intensive Care and expanding range of immune suppression (AIDS, transplantation, cancer chemotherapy) has contributed to an expanding range of yeast pathogens and disease syndromes.

Gideon Guide to Medically-Important Yeasts, 2015 contains 131 pages as a 1.08 MB PDF.  The text includes taxa which have been described in only a single country, or even a single patient.  For each taxon, the ecology and disease association are described, followed by typical phenotype and drug susceptibility pattern, and a listing of older taxonomic designations (921 names as of 2015).

Order the Yeast Guide now for only $39.99

Use the temporary code of “hardy10” to receive a 10% discount.

Respect your elders…
They made it through school
without Google or Wikipedia!


Pun Zone Ahead

  • Horton has a photographic memory. Trouble is…it was never developed.
  • When a clock is hungry it goes back four seconds.
  • Bob fell onto an upholstery machine. Thankfully, he is now fully recovered.
  • When Mildred saw her first strands of grey hair she thought she’d dye.
  • Dexter, the photographer, lost several toes in a tragic accident and could no longer work. It’s OK now, he has faux toes.

“Moxly, I’m afraid we have some
discouraging data on the new anti-depressant”

“It is difficult to get a man to understand something,

when his salary depends upon

his not understanding it!”


Upton Sinclair

1878 ~ 1968
American novelist who exposed unsanitary conditions in the meat packing industry

that led to the “Pure Food and Drug Act”

passed by Congress in 1906.

Online Ordering Made Easy!

Online ordering
Watch a short video
to learn how easy it is
to order from Hardy on-line!

Pick . Click. You’re Done!

* * *

“It’s easier to fool people
than to convince them
they have been fooled.”
Mark Twain


* * *

Our Optical Oddity for this month is a photo of the beginnings of a soda bottle. Heat and compressed air are applied to this precursor to create the bottle.