Partnering with microbiologists to diagnose and prevent diseaseTM

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 a culture of service…


March, 2016

© 2016, Hardy Diagnostics,

all rights reserved 

Interference from 
Proteus eliminated!…

Spending too much time with stool cultures?

hardyCHROM ss
Hardy’s unique chromogenic plate will readily differentiate Proteus from Salmonella and Shigella. Get ready for the onslaught of summer stool cultures and stop wasting time working up Proteus!

View more information on HardyCHROM SS

Send me samples, so I can see for myself.

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Hot off the press…

New Culture Media Catalog

Hardy announces its new catalog of all culture media offerings.
This 85 page booklet contains descriptions of the 2,700 products that Hardy manufactures for the microbiologist.
Send me the paper version.
Please have an account rep contact me about a price quote.

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Rapid Strep Grouping

StrepPRO

StrepPRO
Hardy’s StrepPRO will quickly type your strep isolates by latex agglutination. It features a clear and distinct read-out without cross reactivity. It will even give you results for Group D. 
Watch a short video.
Order the kit now.
See the brochure.
View all our latex kits.

*  *  *

Announcement!

Hardy Purchases QuickSlide
We are pleased to announce in January, Hardy Diagnostics completed the purchase of GG&B Company and now offers these products to its customers under the name QuickSlide™. Now Hardy can offer a selection of automated slide stainers for either Gram, AFB, or hematology stains. All of the QuickSlide stainers offer low to no maintenance, patented technology, and great service at a reasonable cost!

 


View the QuickSlide website.


Read the Press Release.


Please contact me to discuss automated slide stainers.

What are they saying about Hardy Diagnostics?
* * *

Foot in Mouth Disease…

Darryl Zanuck
American film producer
1902 ~ 1979

 “Television won’t be able to hold on to any market it captures after the first six months. People will soon get tired of staring at a plywood box every night.”
*  *  *

Compact Dry…

Do you do 
plate counts?


 
If you perform plate counts for the food or beverage industries, you will want to try out the new Compact Dry plates. 
  • Fast and easy inoculation. 
  • No need for a spreader. 
  • Room temperature storage.
  • Simple, colorful chromogenic read-out.
Learn more…

See our complete Food microbiology offering.

Send me your paper food micro catalog.

Please have an account rep prepare a price quote for me.
* * *

  

Brainteasers 

 

Brain

 

 

Build muscle 
between your ears
 here.


All formats available…

Control 
Organisms


Hardy offers a complete selection of microorganisms for your QC program. These MBL organisms are licensed derivatives from ATCC. They are available in the swab or pellet format; qualitative or quantitative. Order from Hardy for immediate service and delivery.
View the entire catalog online.
Request a paper catalog.
Microorganism catalog 2

Think about it…
    
The Thinker

* Why is it when a door is open, it’s ajar, but when a jar is open, it’s not a door?

* Tell a man that there are 400 billion stars, and he’ll believe you. Tell him a bench has wet paint, and he has to touch it.

* How come Superman could stop bullets with his chest but always ducked when someone threw a chair at him?

* If “con” is the opposite of “pro,” then what is the opposite of progress?

* Why is it lemon juice contains mostly artificial ingredients but dish-washing liquid contains real lemons? 

* * *

Wisdom to Ponder…


Bob Hope
1903 ~ 2003
His career as a comedian and actor spanned almost 80 years. He was best known for his 41 tours entertaining US troops with the USO.
“I have seen what a laugh can do. It can transform almost unbearable tears into something bearable, even hopeful.”

“I grew up with six brothers. That’s how I learned to dance – waiting for the bathroom.”

“People who throw kisses are hopelessly lazy.”

“She said she was approaching forty, and I couldn’t help wondering from what direction.”
“You know you’re getting old when the candles cost more than the cake.”

“Middle age is when your age starts to show around your middle.”

“You never get tired, unless you stop and take time for it.”

“I do benefits for all religions – I’d hate to blow the hereafter on a technicality.”

“When we recall the past, we usually find that it is the simplest things – not the great occasions – that in retrospect give off the greatest glow of happiness.”



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Did you know? 

 
 
Hardy Diagnostics…
  • Is celebrating its 36th year of serving microbiologists.
  • Manufactures from two ISO certified factories in California and Ohio. 
  • Is ISO 13485 certified for the manufacture of medical devices to give you confidence in our products.
  • Offers you detailed technical inserts, comprised of over 4,500 pages of information regarding microbiology.
  • Services over 10,000 labs and maintains a worldwide network of over 65 distributors.
  • Is a 100% Employee-Owned company. “If we act like we own the place…it’s because we do!”
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QUICK LINKS…

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As Hardy Diagnostics 
enters its 36th year of serving microbiologists in the laboratory, I would like to thank each of our customers for their support and loyalty. It truly has been a pleasure to serve you!
If there is any way that we can improve or expand upon our service, would you please let me know?

 

Jay's photo 2

Jay Hardy, CLS, SM(NRCM)

President
HARDY DIAGNOSTICS
Micro Musings…
 

Biocemenation:

Can we use bacteria 
to create new habitats 
in the sand?

Find out how. 

 

If you work in the pharmaceutical industry, you won’t want to miss our new catalog that details products for sterility testing and environmental monitoring. It contains lots of good ideas to make your day go more smoothly!
 * * * 
 

  

Online Ordering Made Easy! 

  

Online ordering
Watch a short video
to learn how easy it is
to order from Hardy on-line!

Pick. Click. You’re Done!

  * * *  

Optical oddities… 

 
Which of these three diagrams is different?

  “Believe half of what you see

and none of what you hear.”

 ~ Marvin Gaye ~    

 

Sure hope you said the middle one, 

because that is the one that is different

from the other two!

 

 


Adaptations increase pathogenicity…
Bartonella
 
Bartonella is a bacterial genus capable of causing several human diseases. The three most common are cat scratch disease, caused by B. henselae; trench fever, caused by B. quintana; and Carrión’s disease, caused by B. bacilliformis

Cat scratch disease can be transmitted from the scratches of cats, particularly kittens, due to cats harboring infected fleas that carry Bartonella. Most cats carry the bacteria in their blood without getting sick and some studies have found that 1 out of 3 healthy cats carry Bartonella in their blood. 

Trench fever is transmitted by the human body louse and is most commonly associated with homeless populations or areas of high population density and poor sanitation. In a recent analysis, it was found that about 33% of body lice recovered from infested homeless people were PCR positive for B. quintana

Carrión’s disease is transmitted by bites from sand flies that carry the organism. These infections are endemic in the Andes Mountains in western South America, including Peru, Colombia, and Ecuador. 

Although different Bartonella species have different vectors of transmission and cause different types of infections, what they all have in common is the ability of the Bartonella bacteria to adapt to vastly different host environments. How are these bacteria overcoming stressful changes in their environment, and can the answers to this question lead to development of specific treatment for Bartonella infections?

Dr. Jane Koehler at UC San Francisco has studied the transmission of Bartonella quintana and has found temperature-specific regulation of genes that may confer survival of the organism in its two different hosts, humans and body lice. B. quintana must undergo change in temperature between hosts and a drastic change in hemin concentration between hosts. The louse vector has an internal body temperature of 28°C and very high hemin concentrations in the gut. In contrast, human host temperature is 37°C and the human bloodstream is hemin-restricted. Although hemin is necessary for Bartonella to obtain an iron source, the levels of hemin contained in the louse gut are at toxic levels, producing reactive oxygen molecules that can be lethal to bacteria. B. quintana must contain mechanisms that allow it to survive when exposed to decreased temperatures and increased hemin concentrations in the body louse gut.

Bartonella produces a family of hemin binding proteins (Hbp) that are responsive to temperature, hemin concentration, and oxidative stress. They also produce hemin utilization (Hut) proteins that are involved in hemin sensing, degradation, and storage. Both Hbp and Hut proteins are most likely important players in Bartonella’s ability to survive in a wide range of hemin concentrations.

Wild type B. quintana has greater tolerance of high levels of hemin than what was observed previously for B. henselae. The difference in hemin tolerance displays how evolutionary adaptation allows each Bartonella species to adapt to its specific arthropod vector. Understanding what is essential for Bartonella survival and targeting the vector stage is important for interruption of the body louse to human transmission cycle.


The Antibiotic Apocalypse Explained…
Drug Resistance


 

We have come across a beautifully animated video from Patreon that explains drug resistance in a simple but elegant way. View the video now.

Discussed in the video is how antibiotic resistance oftentimes originates in farm animals. Did you know that 80% of all the antibiotics in America are used for meat-producing animals? Is it any wonder how we got into the resistance mess that we are in today?
* * * 

Environmental Monitoring…
Contact Plates

MRSA Contact Plate

Hardy offers a complete line of 
contact plates for your surface monitoring.
The Tap-Tight feature assures that 
the lids will stay securely in place!
 
View the brochure.

Request samples for evaluation.

Request a price quote.

 

RUBES   

     
 

Find more 

of Leigh Rubin’s cartoon humor. 

Want to book Leigh as a speaker at your next event? 

 


Guess Who?
Below is a Vision and Value statement from 
a famous company. Can you guess who?

Respect
We treat others as we would like to be treated ourselves. We do not tolerate abusive or disrespectful treatment. Ruthlessness, callousness, and arrogance don’t belong here. 

Integrity

We work with customers and prospects openly, honestly, and sincerely. When we say we will do something, we will do it; when we say we cannot or will not do something, then we won’t do it. 

Communication

We have an obligation to communicate. Here, we take the time to talk with one another…and to listen. We believe that information is meant to move and that information moves people. 

Excellence

We are satisfied with nothing less than the very best in everything we do. We will continue to raise the bar for everyone. The great fun here will be for all of us to discover just how good we can really be.

Scroll to bottom for the answer… 
 
 

Warning:
PUN ZONE
ahead
They just found a sword swallower dead.The police suspect it’s an inside job.


 
I was struggling to figure out how lightning works; then it struck me.


 
I don’t mind kids playing hopscotch in most places, but my driveway is where I draw the line.


 
Time flies like an arrow. Fruit flies like a banana.


 
I try wearing tight jeans, but I can never pull it off.


 
I heard the new auto body shop that opened comes highly wreck-a-mended.


 
Did you hear about the celery that was arrested? It was a stalker.


 

Do you do Growth Promotion Studies?


Hardy has the answer to simplified growth promotion studies. MBL’s EZ Accushot provides you with quantified lyophilized organisms that you can count on!

Guess Who?

If you guessed Enron, you would be right. Enron, which went bankrupt in 2001, remains as the best example of systematic, premeditated, pervasive, and planned corporate fraud and stock price manipulation. Most of its 20,000 employees lost their jobs and their life savings due to the unscrupulous activities of Enron’s leaders. 
 
 
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