Partnering with microbiologists to diagnose and prevent diseaseTM

How can the right gut bacteria can improve your health?

 

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a culture of service…

March, 2017

 

© 2017, Hardy Diagnostics,

all rights reserved 

 

 
  Hardy is your distributor 
  for Denka Seiken
 

Antisera

Denka-Seiken

See the brochure.

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Keep the stain where it belongs…
 

No Mess!
No Stress!
Hardy’s GramPRO 1 will rapidly stain your smears and get it right every time! Our patented technology judges the thickness of the smear and adjusts the decolorization step to perfection. Not only that, there are no messy clean-up or maintenance procedures. The GramPRO 1 will produce a perfect slide every time in about 4 minutes.

 

 

 

Find out more about the GramPRO 1.

 

Watch a brief video on GramPRO 1.

 

View the brochure on all of Hardy’s automated stainers.

 

 

Please contact me to discuss automated slide stainers.

 

 

Phraseology…
 
“Cobweb”  
     

The orgin of this word dates back to the 14th century when the Old English word for spider was coppe. To say “coppeweb” or “copweb” was difficult, so it became “cobweb.”
“Cob” as a stand-alone term for “spider” was an old word nearly dead even in dialects when J.R.R. Tolkien revived it use in “The Hobbit” (1937).
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Showing 2,700 products!

 

Hardy’s Culture
Media Catalog

 

Hardy is proud to announce its 2017 catalog of all culture media offerings.
 
This 85 page booklet contains descriptions of the 2,700 products that Hardy manufactures for the microbiologist.
View the digital version.
Send me the paper version.
Please have an account rep contact me about a price quote.

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Hardy’s AloeSafe Sanitizer…
 

 

Don’t you deserve the best?
AloeSafe

 

Hardy’s AloeSafe has many advantages over the cheap drug store hand sanitizers.

 

 

 

 

 

 

 

 

What is Hardy all about?
View a short video to find out…

 

 

 

 

 

 

 

 

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Brainteasers

Brain

  

Need a cranial stimulant?

Think about it…
    
The Thinker

 

 

 

* How come abbreviated is such a long word?

* If it’s zero degrees outside today and it’s supposed to be twice as cold tomorrow, how cold is it going to be?

* Why do you press harder on a remote-control when you know the battery is weak?

* Since Americans throw rice at weddings, do Asians throw hamburgers?

*Why are they called buildings, when they’re already finished? Shouldn’t they be called builts?

 

 

 

 

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Wisdom to Ponder…
   
Socrates
470 BC ~ 399 BC
A classical Greek philosopher 
Credited with being the founder of Western philosophy and ethics
“The only true wisdom is in knowing you know nothing.”
“Worthless people live to eat and drink; people of worth eat and drink only to live.”  
 
“I only wish that ordinary people had an unlimited capacity for doing harm; then they might have an unlimited power for doing good.”
 
“An unexamined life is not worth living.”
 
“I was really too honest a man to be a politician and live.”
 
“By all means, marry. If you get a good wife, you’ll become happy; if you get a bad one, you’ll become a philosopher.”
 
“Let him that would move the world, first move himself.”
 
“I am the wisest man alive, for I know one thing, and that is that I know nothing.”
 
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Online Ordering Made Easy! 

 

 

 

Online ordering

Watch a short video
to learn how easy it is
to order from Hardy on-line!

 

Pick. Click. You’re Done!

 

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Did you know? 

 

 
Hardy Diagnostics…
  • Is celebrating its 36th year of serving microbiologists.
  • Manufactures from three ISO certified factories; one in California, Ohio, and Texas.
  • Is ISO 13485 certified for the manufacture of medical devices to give you confidence in our products.
  • Services over 10,000 labs and maintains a worldwide network of over 65 distributors.
  • Is a 100% Employee-Owned company. “If we act like we own the place…it’s because we do!”

 
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QUICK LINKS…
 

 

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If you are not 
a part of the solution..
You are part of the precipitate!

 

“As Hardy Diagnostics enters its 37th year of serving microbiologists in the laboratory, I would like to thank each of our customers for their support and loyalty. It truly has been a pleasure to serve you!
If there is any way we can improve or expand upon our service, would you please let me know?”
Jay Hardy, CLS, SM(NRCM)
President
HARDY DIAGNOSTICS
Jay's photo 2

 

“Education is what you get 
when you read the fine print…
 
Experience is what you get 
when you don’t.”
Pete Seeger

 

Warning:
PUN ZONE
AHEAD
* I used to have a fear of hurdles, but I finally got over it.
* Did you hear about the man who survived an attack with pepper spray? He’s now a seasoned veteran.
* I’m so glad that I know sign language. It’s so handy!
* Have you heard about the popular new type of broom…It’s sweeping the nation!

 

* Show me a piano falling down a mine shaft and I’ll show you A-flat minor.

 

#  #  #

 

People who hate cats…

 

 
will come back as mice in the next life.
 
 
Micro Musings…
 
 

 
CRE – The Most 
Worrisome Superbug
 
CRE found to be resistant 
to all available antibiotics in the U.S.
It is uncommon in this day and age to find a microbiologist who is unaware of the growing concern of antibiotic resistance but many may still be unfamiliar with the severity of the cases that have been surfacing lately.
In September of 2016, a woman who died from an “incurable infection” was reported in Reno, Nevada. The culprit of the infection was a Carbapenem Resistant Enterobacteriaceae (CRE) identified as Klebsiella pneumoniae, which is a normal commensal of the human gut bacteria and is often a cause of urinary tract infections. This particular CRE showed resistance to 26 different antibiotics, including polymixin (colistin) all aminoglycosides, and intermediately resistant to tigecycline.  It was tested against every antibiotic available in the United States and none were effective to treat this infection. These types of organisms have been coined the term of superbugs due to their resistance to a class of antibiotics typically used as a last line of defense when other antibiotics fail. They also pose the danger of passing on their antibiotic resistance to other organisms thus allowing the spread of antibiotic resistance among the population, particularly in hospitals where many cases are acquired.
Klebsiella are ubiquitous and may colonize the skin, pharynx, or gastrointestinal tract in humans. They form large moist colonies due to “large mucoid polysaccharide capsule (K antigen) that protects from phagocytosis and aids in adherence”
In the case of the Nevada woman, the specific CRE was isolated from a wound specimen collected in August of 2016. The patient had a history of recent hospitalizations in India after breaking her right femur and later developed a bone infection. She presented with systemic inflammatory response syndrome in August and was admitted to the acute care hospital. She went on to develop septic shock and died in early September. Presence of New Delhi metallo-beta-lactamase (NDM) was confirmed in the CRE isolate. NDM enzymes break down carbapenems and make them ineffective. KPC, OXA-48, IMP, and VIM are other mechanisms of antimicrobial resistance commonly found in CRE organisms.
Although CRE in the United States is not altogether uncommon, isolates that are resistant to all antimicrobials are very rare. Most remain susceptible to at least one aminoglycoside and to tigecycline which this particular isolate in Nevada was resistant and intermediately resistant to, respectively.
The CDC  recommends that when these bacteria are identified, appropriate infection control contact precautions be implemented to prevent transmission. In addition, patient contacts should be evaluated for transmission, which was done in the case of the Nevada woman and upon which no additional NDM CRE were found.
by Alani Barajas
R&D Microbiologist
Hardy Diagnostics
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Hardy Diagnostics offers a chromogenic plated media to assist in the detection of CRE. 
 
Klebsiella

 
Keeping your 
gut bacteria happy!
 
Learn more about how your intestinal microbiome affects your overall health.
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Do you perform growth promotion testing? . . .
EZ Accu Shot
  
The MicroBioLogics EZ Accu Shot provides a quantitative solution to your QC and Growth Promotion testing.

More products for easy
Growth Promotion testing
 
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For environmental monitoring . . .
C diff
Banana Broth
Hardy announces a new medium for the detection of
Clostridium difficile bacteria and spores. This new medium is capable of saving hospitals many thousands of dollars. It is useful in monitoring the efficacy of cleaning procedures used in patient rooms. This is the first and only culture medium that is designed for the detection of C. difficile and its spores on surfaces in a hospital setting.  The specificity was found to be 100% in a recent study (see reference below). No special equipment or anaerobic supplies are needed! Obtain results in as little as 24 hours!

View a short video explaining how C. diff Banana Broth can increase the level of patient safety and save your hospital many thousands of dollars!
 
 
 
Request a sample for your evaluation.
 
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A different approach…
 
To finish
or not to finish…
that is the question
I recently had all four of my wisdom teeth removed and the oral surgeon instructed me to finish the entire prescription of Ampicillin in order to kill all of the bacteria that could potentially cause infection of my healing gum tissue. If you have ever had a bacterial infection, or some kind of treatment that could put you at risk for one, you have probably heard that same bit of advice. 
 
According to an article by Lyn Gilbert, Clinical Professor in Medicine and Infectious Diseases from the University of Sydney, a complete dose or prescription of antibiotics could possibly hinder rather than help patients. Gilbert points out that sufficient testing has not been performed yet to determine optimal antibiotic course duration per case of infection. 
 
Historical and current medical cases have shown failures when prescribing an antibiotic for too short of a period of time, leading to relapse of the bacterial infection. However, taking a full course of antibiotics for an extended amount of time, or when unnecessary, can also lead to increased bacterial resistance in hospitals and the community. Also the chances of eliminating friendly bacteria in the gut are increased with longer periods of antibiotic treatment. This can be alleviated by using more narrow-spectrum antibiotics, intended to eliminate only the pathogens. 
 
Gilbert explains that any course of antibiotics, even one that is not very long, can expose normal bacterial flora in or on the human body to selective pressures that favor the proliferation of bacterial resistance mechanisms.
 
Gilbert admits some serious bacterial infections need urgent and quite prolonged treatment; how long depends on the type of infection, how serious it is, the patient’s underlying condition and response to treatment. For example, patients with abscesses, osteomyelitis, prosthetic heart valves, or tuberculosis require a full course of treatment. 
 
Aside from bacterial resistance, there is also a small number of patients who suffer allergic reactions or severe side effects from antibiotics. For example, some patients have experienced tendon rupture when prescribed Ciprofloxacin for a urinary tract infection or other bacterial infection. There are usually alternative antibiotics with lower toxicity or fewer side effects that could work similarly in treating some of these infections.
Other patients may experience anaphylaxis due to an allergic reaction to an antibiotic, such as penicillin. When these side effects are noted by the patient or hospital workers, treatment should be discontinued. Moreover, the patient would need re-evaluation by a medical professional to determine whether or not the antibiotic chosen was the best one or if there is an alternative that could work equally as well.
Antibiotic stewardship programs outlined by the CDC are in place around the world at healthcare facilities. The CDC’s 2016 stewardship report described antibiotic stewardship as, “the effort to measure and improve how antibiotics are prescribed by clinicians and used by patients” (Sanchez). These programs attempt to inform and educate healthcare workers on the negative effects of prescribing antibiotics too readily, prescribing the incorrect antibiotic, or the over-use of broad spectrum antibiotics. They also identify when the decision to prescribe an antibiotic is necessary immediately or if it can wait until after culture results are available. The goal of the stewardship program is to reduce unnecessary antibiotic use by raising awareness of how bacterial resistance is spread.
Although Gilbert’s article was originally published in 2015, it’s impressive to note how much we’ve learned about antibiotic resistance in just two years.  Information on antibiotic resistance is widely available through the internet and knowledge of resistance mechanisms and how resistance can spread is becoming more well-known.
Continual efforts to educate both healthcare professionals and the public may aid in slowing the spread of antibiotic resistance.
by Anna Clavins
R&D Microbiologist
HARDY DIAGNOSTICS
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Trio Bas
Air Samplers
 
Two heads are better than one!
 
Now with Bluetooth capability!
Trio Bas from Orum International has a robust impact air sampler for every type of use. Single, double, or triple heads are available from Hardy Diagnostics.
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   Optical oddities… 

 

See a flock of doves?
Squint your eyes and you will see something else…

 

 

 

 

  “Believe half of what you see

and none of what you hear.”

 ~ Benjamin Franklin ~

 
MycoVue
 
Do Not Disturb!

MycoVue  
 
Fungal slide cultures made easy!
 
Hardy’s  MycoVue takes out all the tedious labor of preparing a professional slide culture.
Just inoculate the agar cube, place the cover slip on top, incubate, and place the entire unit on the microscope stage for easy examination.
The fungal culture can be observed without disturbing the delicate structures. 

 

RUBES

   

Find more

of Leigh Rubin’s cartoon humor.

Want to book Leigh as a speaker at your next event?

You really shouldn’t be tailgating me
when I’m going 50 in a 30mph zone.
And, by the way, those lights 
on top of your car look ridiculous!