Vol. 1, Issue 6 ‣ September 2024
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Reducing Risk with Strep B Carrot Broth™: Combatting Newborn GBS Infections
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The birthrate in the United States has hit a new record low, according to an analysis of 2023 birth certificate data published this past spring by the Centers for Disease Control and Prevention (CDC). Last year’s slowdown marks an end to the uptick in new births that began during the COVID-19 pandemic. At least 3,591,328 babies were born in the U.S. in 2023, down 2% from the 3,667,758 born in 2022. Prior to the pandemic, U.S. birthrates continued to decline with an average of about 2% fewer babies each year.
This is on par with the global birthrate, which fell from 4.84 in 1950 to 2.23 in 2021. Predictions point to a continuing drop in birth rates to 1.59 in 2100.
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Figure 1. Number of live births and general fertility rates: United States, final 2000–2022 and provisional 2023
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“What we are experiencing now, and have been experiencing for decades, is something that we have not seen before in human history, which is a large-scale, cross-national, cross-cultural shift towards preferring and having smaller families,” said Dr. Jennifer D. Sciubba, a demographer and author of 8 Billion and Counting: How Sex, Death, and Migration Shape Our World.
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The birth rate is one of the most important determinants of a country’s population growth, potentially impacting policy decisions about the health system, education, and economy.¹
A previous analysis by the Institute for Health Metrics and Evaluation published in the Lancet in 2020 predicted that the world population will peak in 2064 at around 9.7 billion and then decline to 8.8 billion by 2100. Another projection by the UN World Population Prospects 2022 predicted world population to peak at 10.4 billion in the 2080s.
“Regardless of the exact timing of peak world population, it will likely begin declining in the second half of the century," Sciubba said, "with dramatic geopolitical, economic and societal consequences.”
While we wait to see if these predictions are correct or not, count back nine months, and it's worth noting that most conceptions occur in the fall and winter. That matches up with the CDC’s data suggesting that August and September are among the most popular birth months.
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In an ongoing effort to protect all newborns, Hardy Diagnostics continues to create innovative products to aid in women’s health care. One of Hardy’s most unique and colorful products to detect Group B Streptococcus in pregnant women is Strep B Carrot Broth™ One-Step (Cat. no. Z40). In the United States, Group B Streptococcus or GBS is a leading cause of meningitis, pneumonia, and bloodstream infections in a newborn’s first three months of life.
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Two to three in every 50 cases of newborn GBS infections are fatal. The American College of Obstetricians and Gynecologists, the CDC, and the American Academy of Pediatrics recommend that pregnant women should be screened for GBS colonization between 36 and 38 weeks of gestation.
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Sources:
1 Grundy E, Murphy M. Demography and public health. In: Detels R, Gulliford M, Karim QA, Tan CC, editors. Oxford textbook of global public health. 6th ed. Oxford, England: Oxford University Press, 718–35. 2015.
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Product Spotlight: Strep B Carrot Broth™ One-Step + GBS Detect™
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Strep B Carrot Broth™ One-Step
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Strep B Carrot Broth™ One-Step is a selective and differential medium which is intended for the detection of Group B Streptococcus (GBS), also known as Streptococcus agalactiae, from anovaginal specimens collected from pregnant women. The medium is used as an aid in the qualitative determination of GBS colonization in pregnant women. The color change reaction from white to orange is representative of a positive result for presence of hemolytic GBS.
Our one-step test is an improvement over conventional methods by increasing sensitivity, decreasing turn-around time, and lowering overall cost. Positives require no follow up testing!
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Advantages of Strep B Carrot Broth™ One-Step:
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- One Step
Easy one-step process! Place sample directly in the tube.
- Simple read-out
Development of any orange to red color whatsoever, indicates a positive result.
- Accurate results
For positives, there is no need for further sub-culturing or testing.
- Low cost
Lower overall cost when compared to LIM broth.
- Easy to use
Can be used with liquid and gel-based transport systems.
- Multiple formats
Carrot Broth media is available in multiple formats that work on many automated inoculating machines, such as the WASP®, BD Innova® and Kiestra™.
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Advantages of GBS Detect™:
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GBS Detect™ is recommended for the isolation and differentiation by enhanced hemolysis of detection of gamma-hemolytic (non-hemolytic) Group B Streptococcus from GBS enrichment broth procedures.
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- Optically clear polystyrene
For distortion free viewing.
- Heavy-Duty
Reduces breakage during shipping.
- Stacking rings
Polystyrene Petri plates feature raised rings for stacking ability and prevents sliding.
- Breathable Packaging
Packaged in sleeves of 10 plates in a "breathable" bag that prevents buildup of condensation and excess moisture.
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Thank you to all who came to visit us at ADLM in Chicago in July. See you next year!
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Quick Facts: Group B Strep and Carrot Broth™
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Streptococcus agalactiae (Group B Strep) and Neonatal Infections
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Group B Streptococcus (GBS), or Streptococcus agalactiae, is a leading cause of neonatal infections such as sepsis, pneumonia, and meningitis. Rapid and accurate detection is critical in preventing these life-threatening conditions, especially during the perinatal period.
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Carrot Broth's Unique Role in GBS Detection
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Carrot Broth™ is a selective enrichment broth specifically designed to enhance the detection of GBS in clinical samples. Its formulation, rich in nutrients, supports the growth of GBS, while its color-changing properties enable easy identification, with GBS colonies producing an orange pigmentation.
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Historical Milestones in GBS Detection
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The implementation of Carrot Broth™ has marked a significant advancement in the screening of GBS, particularly in prenatal care. This medium was developed to improve the accuracy and speed of GBS detection, contributing to a decline in neonatal GBS infections.
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Carrot Broth™ and the CLSI Standards
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Carrot Broth™ aligns with the Clinical and Laboratory Standards Institute (CLSI) guidelines for the detection of GBS. Its use in clinical settings is supported by studies demonstrating its sensitivity and specificity, making it a reliable choice for GBS screening.
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Video/Catalog Spotlight: Carrot Broth™
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See our collection of Carrot BrothTM and Prepared Culture Media Videos and Catalogs
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Carrot Broth™ One-Step: Group B Strep Testing for Pregnant Women
Our exclusive Step B Carrot Broth™ One-Step system allows for faster results for the cultivation and identification of beta-hemolytic strains of Group B Streptococcus in pregnant women.
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Megan is an award-winning journalist, marketer, and current Clinical Microbiology Laboratory Marketing Product Manager at Hardy Diagnostics, brings over 20 years of experience in brand management, healthcare marketing, and communications to her role.
If you have any suggestions for content, a comment, or a question, please contact Megan here.
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"A Culture of Service" Hardy Diagnostics, 1430 West McCoy Lane, Santa Maria, CA, 93455, USA, +1.800.266.2222
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