Quality manufactured for a clean, fiber-free opening. SPS Medical pouches are FDA and ADA approved for use with steam, EO gas and chemical vapor processes. White paper that can be sterilized, constructed with 45lb medical grade paper, with see-through heat resistant 2½ mil blue poly-film and a large seal area to prevent blowouts. Each self-seal pouch offers instant sealing and comes with chemical indicators that change color when processed.