Two self-contained units of a single organism

Strain Characteristics:

• Colistin-resistant
• MCR-1 positive

Harbors other resistance genes:

• BlaTEM-1: Broad-spectrum beta-lactamase. Confers resistance to penicillins and first generation cephalosphorins.
• BlaCTX-M-27: Beta-lactamase
• aadA1: Aminoglycoside nucleotidyltransferase gene. Active against aminoglycoside antibiotics.
• aadA2: Aminoglycoside nucleotidyltransferase gene. Active against aminoglycoside antibiotics.
• aac(3)-IIa: Aminoglycoside nucleotidyltransferase gene. Active against aminoglycoside antibiotics.
• lnuF: Lincosamide nucleotidyltransferase. Active against lincosamides (e.g. clindamycin)
• mph(A): Encodes for resistance enzyme MPH(2')-I. Active against macrolide antibiotics.
• dfrA14: An integron-encoded dihydrofolate reductase, active against diaminopyrimidine antibiotics (e.g., trimethoprim).
• tet(A): A tetracycline efflux pump.
• sul1: A dihydropteroate synthase. Active against sulphonamide antibiotics.
• sul3: A dihydropteroate synthase. Active against sulphonamide antibiotics.
• floR: A plasmid or chromosome-encoded chloramphenicol exporter.