Case & Study Reviews
-
February 12, 2018Posted: February 12, 2018Read MoreAntibiotic development has had its challenges recently; and while the concern of drug-resistant Gram-negative has been vastly described since the past couple of decades, there is a growing light at the end of the tunnel with the recent approval of the broad spectrum antimicrobials between 2015-17. Even more encouraging is the potential regulatory filing and approval of several antimicrobial candidates...
-
January 26, 2018Posted: January 26, 2018Read More
Fluoroquinolones have been the staple of antimicrobial therapy since the launch of the flagship representative "Ciprofloxacin" by Bayer in the early 1980s.Fluoroquinolones have a fluorine atom attached to the core quinolone molecular ring and this modification results in a class of broad-spectrum bactericidal agents that show increased stability and potency against both
... -
November 24, 2017Posted: November 24, 2017Read MoreOctober is National Breast Cancer Awareness month, and while breast cancer is the most prevalent cancer among women worldwide, more than half the women who develop this cancer have no known risk factors. The risk factors that are known are not always good predictors of developing breast cancer, including those who are genetically predisposed and those who are exposed to known environmental risk factors... -
November 10, 2017Posted: November 10, 2017Read MoreAs we progress through the 21st Century, the looming threat of antimicrobial resistance and the urgent call for action have been expressed by the medical community worldwide. Bacterial resistance mechanisms are becoming increasingly more common, especially to broad spectrum beta (β)-lactam antibiotics which include penicllins, cephalosporins, monobactams, and carbapenems.
...
-
October 27, 2017Posted: October 27, 2017Read MoreThe classic bulls-eye rash is one that most people are warned to watch out for and are told to seek medical assistance if it appears on the skin. This rash is called erythema migrans and may occur from infection with a bacterium of the genus Borrelia. These bacteria are spirochetes and have a flagellum that aids in mobility. Borrelia burgdorferi is the most common species associated wi... -
October 13, 2017Posted: October 13, 2017Read MoreAmidst the myriad of effects we've found our gut microbiome can have on our daily lives, a recent study finds that it may also affect behaviors in our offspring, even long after they've exited the womb.Two newer studies using rats published by MIT and the University of Massachusetts Medical School explored the idea that the microbial population of the mother's gut can result... -
October 06, 2017Posted: October 06, 2017Read More
On September 6th, 2017, the organization known as PETA or the People for the ethical treatment of animals called out to their vegan brethren to donate their stool…for SCIENCE! [1] For those who are unaware, Fecal Microbiota Transplants or FMT’s are a relatively new but promising treatment for individuals who have had their guts ravaged by the pathogenic bacte...
-
September 22, 2017Posted: September 22, 2017Read More
A vaginal epithelial cell infected with multiple Gram negative and positive bacterial species including G. vaginalis, indicative of Bacterial Vaginosis (BV).Urinary tract infections are a result of bacteria entering the urinary tract through the urethra. When these bacteria arrive at the bladder, they begin to multiply, leading to an infection. In most cases, the urinary system can usually...
-
August 11, 2017Posted: August 11, 2017Read MoreConcerns about antimicrobial resistance have been growing for many years. At one point it seemed as though we were out of options -organisms were becoming resistant to all antibiotics on the market and no new drugs were being produced. A healthy return on investment for an antibiotic was lacking. The cost to develop a new drug is currently over $1 billion. Bacteria would become resistant and make the... -
May 08, 2017Posted: May 08, 2017Read MoreIf one antibiotic resistant bacteria that makes the news often, it is MRSA. Whether it be the recent
infection of newborns at a major clinic or the infection of a national football team due to improper cleaning of gym equipment, MRSA accrues a lot of airtime. MRSA stands for methicillin-resistant Staphylococcus aureus. Staphylococcus aureus is most commonly...
-
October 25, 2016Posted: October 25, 2016Read MoreThe average soccer ball is about 1.6 million times bigger than a grain of sand. A grain of sand is about a million times
bigger than a single
bacterial cell, and a single bacterial cell can be 40 to 100 times bigger than a norovirus... -
June 15, 2016Posted: June 15, 2016Read MoreGiven the prevalence of hospital-acquired infections (HAIs) in the United States, several companies are making efforts to develop technologies to reduce the occurrence of HAIs. In a multistate point-prevalence survey of health care-associated infections in published in 2014, it was estimated that there were about 648,000 patients with 721,800 health care-associated infections in U.S. acute care...
-
August 28, 2015Posted: August 28, 2015Read MoreOn September 13th, 2009 a University of Chicago researcher, Malcom Casadaban, was admitted to a local hospital due to fever, aches, cough and shortness of breath. Blood tests indicated renal failure, severely elevated white blood cell count, and a left shift in the ratio of immature to mature neutrophils. Blood smears indicated bacteremia. The patient was treated with vancomycin and pipercillin/tazobactam...
