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Clinical

  1. December 01, 2017

    Is it Viral or Bacterial?

    In an attempt to reduce the inappropriate use of antibiotics, researchers at the University of Rochester have developed a tool that physicians can use to distinguish between a bacterial or viral infection in a patient that is suffering from an infection. Antibiotics are useless in treating viral infections; sadly, bacterial resistance is stimulated by the indiscriminate and often unnecessary use of...

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  2. November 24, 2017

    Can Microbiome Have an Influence on Breast Cancer?

    October is National Breast Cancer Awareness month, and while breast cancer is the most prevalent cancer among women worldwide, more than half the women who develop this cancer have no known risk factors. The risk factors that are known are not always good predictors of developing breast cancer, including those who are genetically predisposed and those who are exposed to known environmental risk factors...
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  3. November 17, 2017

    How To Avoid Infecting Your Thanksgiving Guests

    In September 1620, a group of separatists seeking religious freedom of worship as well as bountiful land sailed from Plymouth, England for the New World. After a 66 day journey, the Mayflower dropped anchor off the coast of Cape Cod, nearly 200 miles north of their intended destination.  They of course, in true European fashion, named their new colony Plymouth after their departing port.

    The...

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  4. November 10, 2017

    Resistance to β-Lactam Antibiotics: New Solutions to an Old Problem  

    As we progress through the 21st Century, the looming threat of antimicrobial resistance and the urgent call for action have been expressed by the medical community worldwide.  Bacterial resistance mechanisms are becoming increasingly more common, especially to broad spectrum beta (β)-lactam antibiotics which include penicllins, cephalosporins, monobactams, and carbapenems....

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  5. October 27, 2017

    Transmission of Lyme Disease by Mosquitos and Flies

    The classic bulls-eye rash is one that most people are warned to watch out for and are told to seek medical assistance if it appears on the skin. This rash is called erythema migrans and may occur from infection with a bacterium of the genus Borrelia. These bacteria are spirochetes and have a flagellum that aids in mobility. Borrelia burgdorferi is the most common species associated wi
    ...
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  6. October 13, 2017

    Can Mother's Microbiome Affect Her Child's Behavior?

    Amidst the myriad of effects we've found our gut microbiome can have on our daily lives, a recent study finds that it may also affect behaviors in our offspring, even long after they've exited the womb.
    Two newer studies using rats published by MIT and the University of Massachusetts Medical School explored the idea that the microbial population of the mother's gut can result
    ...
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  7. October 06, 2017

    Fecal Microbiota Transplants and C. difficile

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    On September 6th, 2017, the organization known as PETA or the People for the ethical treatment of animals called out to their vegan brethren to donate their stool…for SCIENCE! [1]  For those who are unaware, Fecal Microbiota Transplants or FMT’s are a relatively new but promising treatment for individuals who have had their guts ravaged by the pathogenic bacte...

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  8. September 22, 2017

    Does Gardnerella vaginalis Play an Important Role in Urinary Tract Infections?

    A vaginal epithelial cell infected with multiple Gram negative and positive bacterial species including G. vaginalis, indicative of Bacterial Vaginosis (BV).

    Urinary tract infections are a result of bacteria entering the urinary tract through the urethra. When these bacteria arrive at the bladder, they begin to multiply, leading to an infection. In most cases, the urinary system can usually...

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  9. September 15, 2017

    Saving a Baby One Broth at a Time

    My wife is eight months pregnant and her due date is creeping ever closer with each passing day. In this last month, many preparations are being made in our home. We have assembled the cradle, put away the copious amount of clothes our generous parents have given us (it's our first child), and the house has never been so clean. My wife is also making her own personal preparations. She is eating extremely...

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  10. August 11, 2017

    New antimicrobials on the way…

    Concerns about antimicrobial resistance have been growing for many years. At one point it seemed as though we were out of options -organisms were becoming resistant to all antibiotics on the market and no new drugs were being produced. A healthy return on investment for an antibiotic was lacking. The cost to develop a new drug is currently over $1 billion. Bacteria would become resistant and make the...
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  11. May 08, 2017

    Merciless MRSA

    If one antibiotic resistant bacteria that makes the news often, it is MRSA. Whether it be the recent

    infection of newborns at a major clinic or the infection of a national football team due to improper cleaning of gym equipment, MRSA accrues a lot of airtime. MRSA stands for methicillin-resistant Staphylococcus aureus. Staphylococcus aureus is most commonly...

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  12. April 17, 2017

    No Proteus? No Problem!

    In 1968, Hektoen Enteric (HE) Agar was introduced by the Hektoen Institute of Chicago. HE agar is a selective and differential agar used for the culture of Salmonella and Shigella from patient stool samples. HE agar contains indicators of lactose fermentation and hydrogen sulfide production, while possessing inhibitors to prevent the growth of Gram-positive bacteria.

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  13. March 29, 2017

    Serogrouping of Strep:The Legacy of Rebecca Lancefield

    Some species of streptococci are unique in that they are classified or grouped according to the antigenic structure of their cell walls. Ever wondered how this was discovered? In this article, we will explore the history of how strep grouping came to be in common usage today.

    The genus Streptococcus contains many pathogens from numerous body sites. Over 50 species of these gram-positive cocci...

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  14. March 06, 2017

    Honoring one of the greatest antibiotic researchers… H. Boyd Woodruff

    Boyd Woodruff was the son of an East Coast farmer whose ground-breaking research served as a lynch pin for fellow scientists to be able to harvest a plethora of lifesaving antibiotics from every day soil.

    Known simply as Boyd, he loved to read and explore the world around him. However, it was not until he was a senior in high school and had to take chemistry that he discovered his true passion...

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  15. March 03, 2017

    The Difficulties of C. difficile

    With Clostridium difficile infections (CDI) on the rise among hospital acquired infections across America in hospitals and care facilities, infection control specialists have been scrambling to prevent the acceleration of this toxic and destructive bacterium. Where does CDI come from? Where is it going? How can we avoid it? With nearly half a million impacted yearly from this infection...

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