Industry Insights
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Posted: May 11, 2018
Recently, cases of cholangiocarcinoma (bile duct cancer) and hepatic pain in the United States have been described among Vietnam War veterans. The cause is Clonorchis sinensis, one of the most prevalent parasites in the world which is still transmitted in many regions of Asia. It is also known as the liver fluke worm. The fluke worm, Opisthorchis viverrini is another potential
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Posted: April 27, 2018
In recent years, greater appreciation for microbes inhabiting human body sites has emerged. In the female mammary gland, milk has been shown to contain bacterial species, reaching the ducts from the skin. Researchers have also discovered a diverse population of bacteria within tissue collected from sites all around the breast in women ages 18 to 90, not all of whom had a history of lactation...
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Posted: April 06, 2018
While GBS screenings are the standard in the US and in Europe, there are still parts of the world where the 1 in 5 women globally who carry GBS may not receive screening or treatment. The Bill and Melinda Gates Foundation funded a study led by the London School of Hygiene and Tropical Medicine, involving more than 100 researchers who published a series of 11 research papers reporting on GBS occurances...
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Posted: February 12, 2018
Antibiotic development has had its challenges recently; and while the concern of drug-resistant Gram-negative has been vastly described since the past couple of decades, there is a growing light at the end of the tunnel with the recent approval of the broad spectrum antimicrobials between 2015-17. Even more encouraging is the potential regulatory filing and approval of several antimicrobial candidates...
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Posted: January 26, 2018
Fluoroquinolones have been the staple of antimicrobial therapy since the launch of the flagship representative "Ciprofloxacin" by Bayer in the early 1980s.Fluoroquinolones have a fluorine atom attached to the core quinolone molecular ring and this modification results in a class of broad-spectrum bactericidal agents that show increased stability and potency against both
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Posted: December 01, 2017
In an attempt to reduce the inappropriate use of antibiotics, researchers at the University of Rochester have developed a tool that physicians can use to distinguish between a bacterial or viral infection in a patient that is suffering from an infection. Antibiotics are useless in treating viral infections; sadly, bacterial resistance is stimulated by the indiscriminate and often unnecessary use of...
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Posted: November 10, 2017
As we progress through the 21st Century, the looming threat of antimicrobial resistance and the urgent call for action have been expressed by the medical community worldwide. Bacterial resistance mechanisms are becoming increasingly more common, especially to broad spectrum beta (β)-lactam antibiotics which include penicllins, cephalosporins, monobactams, and carbapenems....
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Posted: October 27, 2017The classic bulls-eye rash is one that most people are warned to watch out for and are told to seek medical assistance if it appears on the skin. This rash is called erythema migrans and may occur from infection with a bacterium of the genus Borrelia. These bacteria are spirochetes and have a flagellum that aids in mobility. Borrelia burgdorferi is the most common species associated wi...
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Posted: September 15, 2017
My wife is eight months pregnant and her due date is creeping ever closer with each passing day. In this last month, many preparations are being made in our home. We have assembled the cradle, put away the copious amount of clothes our generous parents have given us (it's our first child), and the house has never been so clean. My wife is also making her own personal preparations. She is eating extremely...
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Posted: August 11, 2017Concerns about antimicrobial resistance have been growing for many years. At one point it seemed as though we were out of options -organisms were becoming resistant to all antibiotics on the market and no new drugs were being produced. A healthy return on investment for an antibiotic was lacking. The cost to develop a new drug is currently over $1 billion. Bacteria would become resistant and make the...
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Posted: May 08, 2017
If one antibiotic resistant bacteria that makes the news often, it is MRSA. Whether it be the recent
infection of newborns at a major clinic or the infection of a national football team due to improper cleaning of gym equipment, MRSA accrues a lot of airtime. MRSA stands for methicillin-resistant Staphylococcus aureus. Staphylococcus aureus is most commonly...
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Posted: March 03, 2017
With Clostridium difficile infections (CDI) on the rise among hospital acquired infections across America in hospitals and care facilities, infection control specialists have been scrambling to prevent the acceleration of this toxic and destructive bacterium. Where does CDI come from? Where is it going? How can we avoid it? With nearly half a million impacted yearly from this infection...
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Posted: June 15, 2016
Given the prevalence of hospital-acquired infections (HAIs) in the United States, several companies are making efforts to develop technologies to reduce the occurrence of HAIs. In a multistate point-prevalence survey of health care-associated infections in published in 2014, it was estimated that there were about 648,000 patients with 721,800 health care-associated infections in U.S. acute care...